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. 2017 Feb 10;11:59. doi: 10.3389/fnins.2017.00059

Figure 4.

Figure 4

Induced local changes in synchronization around the IES, examples of patients 2 and 4. (A) On the top, results of the averaging of the selected IES. Bellow, Significant statistic (p < 0.0002) results of time frequency analysis in regard of the electrode C2 for patient 2 (on the left) and patient 4 (on the right) (reference period [−1000; −600 ms]). (B) Raw data of time frequency analysis for the patient 2 (on the left) and 4 (on the right) (reference period: [−3000; −1000 ms]). For patient 2, ITFR showed mirrored desynchronization around T0 for frequencies range from 4 to 50 Hz independently of the baseline considered [−1000; −600 ms] (A) or [−3000 ms; −1000 ms] (B). This desynchronization was localized nearly of the epileptogenic zone. For patient 4, a progressive increase in synchronization mirrored around the IES, in the same frequencies were found [baseline [−1000; −600 ms] (A) or [−3000 ms; −1000 ms] (B)]. T0: define by the peak of the first negative deflexion of the IES.