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. 2017 Feb 10;11:59. doi: 10.3389/fnins.2017.00059

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Copyright © 2017 Bourel-Ponchel, Mahmoudzadeh, Berquin and Wallois.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Distant changes in synchronization (G_TFR and I_TFR) around IES. (A) Source localization and dipole fit and SSLOFO in a 3D representation for the patient 8. (B) Statistical significant results (p < 0.0002) of time frequency analysis [induced (I_TFR) and global (G_TFR) time frequency results] in regard of the epileptogenic focus (electrode C5). (C) Statistical significant results (p < 0.0002) of time frequency analysis [induced (I_TFR) and global (G_TFR) time frequency results] in regard of the frontal area (electrode AF4). In I_TFR and G_TFR distant desynchronizations were observed, distant to the epileptogenic zone, notably in fronto-temporal areas, involving low frequency bands (bellow 10 Hz) (C) in the same time window as local dysregulation of synchrony (B) (Figure 3) [−400 ms; +400 ms].