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. 2015 Jan 3;1(2):203–221.e3. doi: 10.1016/j.jcmgh.2014.12.003

Figure 2.

Figure 2

IL33 mRNA expression in the stomach increases after acute H pylori infection and steadily decreases with more chronic infection. (A) IL33 mRNA expression after H pylori SS1 infection in mice; (i) 1 day, (ii) 7 days, and (iii) 2 months relative to uninfected mice and standardized to the housekeeper L32 (N ≥ 6) (repeated twice). (B) IL33 mRNA expression in human biopsy specimens positive for H pylori infection relative to uninfected biopsy specimens and standardized to the housekeeper L32; (i) antrum and (ii) midbody (N ≥ 12). (C) Co-localization of IL33 with UEA1 in H pylori–SS1–infected mice: (i) control, (ii) 7 days, and (iii) 2 months (N = 5). (D) mRNA expression of (i) Muc5AC and (ii) TFF2 after 1 day, 7 days, and 2 months of H pylori–SS1 infection, and standardized to the housekeeper L32 (N ≥ 6). (E) Expression of the ILC2 genes: (i) RORα, (ii) amphiregulin, and (iii) IL13 after 1 day, 7 days, and 2 months of H pylori–SS1 infection, and standardized to the housekeeper L32 (N ≥ 6). ∗Statistically significant, P ≤ .05.