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. 2015 Aug 17;14(2):192–202. doi: 10.1038/cmi.2015.61

Figure 1.

Figure 1

Increased CD180-negative B cells and decreased overall CD180 expression in B cells from SLE patients and MRL/lpr mice. (a) Flow cytometric analysis of the CD180-negative B-cell population within PBMCs from active SLE patients (n = 10) and healthy donors (n = 10). (b) qPCR analysis of CD180 expression in CD19+ B cells of active SLE patients (n = 10) and healthy donors (n = 10). (c) Flow cytometric analysis of the CD180-negative B-cell population in the spleens of MRL/lpr mice (n = 13) and wild-type B6 mice (n = 13). (d) qPCR analysis of CD180 expression in splenic B cells from MRL/lpr mice (n = 13) and wild type mice (n = 13). Error bars represent the SEM. *p  <  0.05, **p  <  0.01, ***p  <  0.001, as determined by t-test; ns denotes p  >  0.05.