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. 2015 Aug 17;14(2):203–213. doi: 10.1038/cmi.2015.66

Figure 3.

Figure 3

Functional changes of the dNK subsets at different gestation stage. (a) Representative dot plots of IFN-γ and CD107a expression by dNK cells from 10.5 and 15.4 weeks of gestation. Decidual leukocytes were cultured for 4 hours with a cell stimulation cocktail and CD107a antibody, then the cells were collected and processed with intracellular IFN-γ staining. Viable CD45+CD56+CD16− dNK cells were gated and studied. (b) Percentages of IFN-γ, CD107a positive dNK cells at different gestational stages of pregnancy. n = 18 (first trimester; 9 ± 1.6 week) or n = 12 (second trimester; 16 ± 1.3 week). The representative plots were from a 14th week decidua. (c) IFN-γ and CD107a expression of different dNK subsets based on their NKp80, NKG2D profile. *p < 0.05.