Table-2.

Liver functional biomarkers in different groups of rats.

Group	Control	APAP control	APAP+SLM	APAP+RTN
Total protein concentration (g/dl)
Day 4	8.41±0.18	4.83±0.50*	4.83±0.56*	4.81±0.65
Day 15	8.43±0.59	4.81±0.78*	7.76±0.72	7.28±0.73
Total bilirubin concentration (mg/dl)
Day 4	0.75±0.01	1.38±0.01*	1.36±0.00*	1.35±0.01*
Day 15	0.83±0.00	1.37±0.00*	0.85±0.01	0.89±0.01
Glucose concentration (g/dl)
Day 4	82.28±0.58	117.38±0.77*	115.08±0.77*	116.39±0.73*
Day 15	85.19±1.00	111.78±3.70**	96.85±1.10*	98.74±0.52*
ALT activity (IU/L)
Day 4	37.27±0.63	92.16±0.59*	89.06±0.47*	90.12±0.55*
Day 15	36.32±0.73	93.24±0.67**	58.38±0.63*	62.64±0.48*

Values are mean±SE (n=6); one-way ANOVA (SPSS),

^*p<0.05,

^**p<0.01 in relation to group 1 (Duncan’s multiple comparison test). APAP=Acetaminophen, SLM=Silymarin, RTN=Rutin, ALT=Alanine aminotransferase, SE=Standard error, SPSS=Statistical Package for Social Sciences