Erratum
After the publication of this article [1] it was noticed that in Table 2 in the second to last row the data needs to be changed. Please see the updated Table 2 below.
Table 2.
Comparison of baseline and day 7 biomarker values (N=1615)
| Variable | Baseline, median (IQRa) | Day 7, median (IQR) | Change, median (IQRb) | P-value |
|---|---|---|---|---|
| Weight, kg | ||||
| Overall | 84.4 (31.4) | 82.6 (30.4) | -1.4 (1.8) | <.001 |
| Men | 93.2 (32.2) | 92.5 (30.8) | -1.5 (2.2) | <.001 |
| Women | 79.2 (29.0) | 78.0 (28.5) | -1.4 (1.6) | <.001 |
| Total cholesterol, mg/dL | ||||
| Overall | 184 (56) | 162 (49) | -22 (29) | <.001 |
| <150 at baseline | 133 (20) | 126 (127) | -8 (23) | <.001 |
| 150-179 at baseline | 165 (16) | 146 (25) | -20 (24) | <.001 |
| 180-209 at baseline | 193 (14) | 169 (25) | -25 (26) | <.001 |
| 210-239 at baseline | 221 (15) | 188 (28) | -34 (27) | <.001 |
| ≥240 at baseline | 261 (31) | 222 (43) | -39 (29) | <.001 |
| HDL cholesterol, mg/dL (N=1092) | 49 (19) | 40 (16) | -8 (8) | <.001 |
| LDL cholesterol, mg/dL (N=1091) | 107 (49) | 92 (41) | -16 (23) | <.001 |
| Systolic blood pressure, mm Hg | ||||
| Overall | 128 (26) | 120 (23) | -8 (18) | <.001 |
| Elevated (≥140) at baseline | 150 (23) | 136 (18) | -18 (18) | <.001 |
| Normal (<140) at baseline | 120 (18.5) | 114 (20) | -4 (16) | <.001 |
| Diastolic blood pressure, mm Hg | ||||
| Overall | 80 (16) | 74 (12) | -4 (10) | <.001 |
| Elevated (≥90) at baseline | 94 (10) | 83 (12) | -11 (11) | <.001 |
| Normal (<90) at baseline | 76 (10) | 70 (13) | -3 (10) | <.001 |
| Triglycerides, mg/dL | ||||
| Overall | 118 (89) | 118 (86) | +2 (48) | .344 |
| Normal (<150) | 92 (49) | 98 (53) | +8 (34) | <.001 |
| Borderline high (150-199) | 169 (22) | 157.5 (73.5) | -11.5 (70.5) | .004 |
| High (200-499) | 247 (81) | 216 (102) | -46 (100) | <.001 |
| Very high (≥500) | 569 (109) | 360 (98) | -294 (131) | <.001 |
| Glucose, mg/dL | ||||
| Overall | 92 (19) | 89 (15) | -3 (11) | <.001 |
| <100 | 88 (9) | 86 (9) | -1 (7) | <.001 |
| 100 to 126 | 107 (10) | 99 (13) | -8 (18) | <.001 |
| >126 | 156 (72) | 149 (84) | -17 (45) | <.001 |
| Blood urea nitrogen, mg/dL | ||||
| Overall | 12 (5) | 9 (4) | -3 (4) | <.001 |
| <10 | 8 (2) | 7 (3) | -1 (2) | <.001 |
| 10 to 20 | 13 (4) | 9 (3) | -4 (3) | <.001 |
| >20 | 23 (6) | 14 (7) | -10 (5) | <.001 |
| Creatinine, mg/dL | ||||
| Overall | 0.8 (0.3) | 0.8 (0.3) | 0 (0.1) | <.001 |
| <1 | 0.8 (0.2) | 0.8 (0.2) | 0 (0.1) | 0.100 |
| 1 to 1.4 | 1.0 (0.2) | 1.0 (0.1) | 0 (0.1) | <.001 |
| >1.4 | 1.6 (0.3) | 1.5 (0.3) | 0.1 (0.2) | 0.002 |
| 10-year risk for hard ASCVD, % (N=1092) | 4.4 (11.4) | 3.9 (9.9) | -0.2 (1.6) | <.001 |
| Patients with elevated risk at baseline, percentage points (N=403) | 18.0 (17.5) | 16.2 (16) | -2.0 (4.1) | <.001 |
aIQR = interquartile range
bNotice that the change column is not the difference between the baseline and day 7 medians. The change score provided by the Wilcoxon signed rank test reflects the paired difference in the 2 scores
Footnotes
The online version of the original article can be found under doi:10.1186/1475-2891-13-99.
Reference
- 1.McDougall J, Thomas LE, McDougall C, Moloney G, Saul B, Finnell JS, et al. Effects of 7 days on an ad libitum low-fat vegan diet: the McDougall Program cohort. Nutr J. 2014;13:99. doi: 10.1186/1475-2891-13-99. [DOI] [PMC free article] [PubMed] [Google Scholar]