Table 1.
Diagnostic sensitivity of some biomarkers in inflammatory myopathies
| Diseases | Markers | Sensitivity (%) | Specificity (%) | ||
|---|---|---|---|---|---|
| Controls | |||||
| All | β-actin | PKM2 | βF1/Hsp60 | 96 | 100 |
| DM | PKM2 | 100 | 100 | ||
| sIBM | β-actin | βF1/LDHA | 100 | 100 | |
| DM | |||||
| All | βF1/PKM2 | 95 | 100 | ||
| CTR | 100 | 100 | |||
| PM | 100 | 100 | |||
| sIBM | 90 | 100 | |||
The table summarizes the power to discriminate (sensitivity) the myopathies by the value of the indicated markers. Sensitivity was calculated accordingly to the classification rate of the positive samples following the formula: Sensitivity = true positives/(true positives + false positives). Specificity = true negatives/(true negatives + false positives)