Figure 3. 430D-F5 inhibits agr activity for all four alleles in a non-biocide manner.

(a) Data are represented as percent agr activity or growth of the vehicle (DMSO) control at 24 hours. The solid lines represent agr activity, measured by fluorescence, and the dashed lines represent growth, measured using OD₆₀₀. See Suppl. Table 3 for additional data. (b) Minimum inhibitory concentrations (MICs) for 430 and lead fractions, reported as μg mL⁻¹.