Table 1.
Patient characteristics, according to donor type
Unrelated recipients | |||
---|---|---|---|
Characteristic | Sibling recipients* (N = 1840) | HLA 16/16–matched† (N = 194) | HLA-DP GVH-mismatched‡ (N = 1023) |
Patient age, median years (range) | 44 (0–74) | 46 (2–75) | 44 (0–78) |
Chronic myeloid leukemia, N (%) | 423 (23) | 57 (29) | 250 (24) |
Female donor for male recipient, N (%) | 502 (27) | 45 (23) | 208 (20) |
Mobilized blood cell graft, N (%) | 909 (49) | 88 (45) | 530 (52) |
At least 900 cGy total body irradiation, N (%) | 691 (38) | 95 (49) | 477 (47) |
Myeloablative conditioning, N (%) | 1552 (84) | 158 (81) | 787 (77) |
HLA-genotypically identical full siblings. Matching includes the entire MHC, including HLA-DPA1 and DPB1.
Matching includes HLA-A, B, C, DRB1, DQA1, DQB1, DPA1, and DPB1.
Matched at HLA-A, B, C, DRB1, DQA1, and DQB1, but GVH-mismatched at HLA-DPA1 or DPB1.