Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
HOTAIR function in regulating HOXD gene expression. Expressed from the HOXC locus, HOTAIR binds to SUZ12 and EZH2, part of the PRC2 complex. HOTAIR acts in trans by recruiting the PRC2 complex to the HOXD locus and silences the locus by establishing H3K27me3 marks (30).
