Table 3.

Information on clusters of significance and peaks showing positive and negative age regressions for OCD and HC during Periodic and Random tasks (Figure 4).

Region (nearest gray matter)	MNI coordinates (x, y, z)			Z score	Cluster Extent	p (peak)
OCD: Periodic – no clusters of significance
OCD: Random – positive regression
Precuneus	−16	−49	39	3.24	4148	0.001
Caudate	21	20	10	2.96	1585	0.002
Extra-nuclear	−21	5	15	2.57	2833	0.005
OCD: Random – negative regression – no clusters of significance
HC: Periodic – positive regression
Precentral gyrus	63	6	3	3.67	2439	0.001
Midbrain	−12	−27	−14	3.37	719	0.001
Insula	−42	5	−9	3.24	2068	0.001
Inferior frontal gyrus	−40	26	12	2.97	1486	0.001
Insula	39	−3	−9	2.97	790	0.002
Sub-gyral	15	42	−14	2.06	632	0.020
HC: Periodic – negative regression
Posterior cingulate	4	−52	10	2.87	764	0.002
HC: Random – positive regression
Putamen	24	12	−6	4.75	81822	0.001
Postcentral gyrus	−57	−16	21	4.42	19076	0.001
Middle temporal gyrus	−45	−57	3	4.23	6419	0.001
Insula	−42	−19	19	3.92	1839	0.001
Caudate	16	9	15	3.91	296	0.001
Middle frontal gyrus	36	44	16	3.75	21528	0.001
Supplementary motor area	9	12	48	3.74	21528	0.001
Thalamus	−16	−12	18	3.05	374	0.001
HC: Random – negative regression
Medial frontal gyrus	−14	52	−5	3.60	2780	0.001
Inferior frontal gyrus	52	28	3	2.93	394	0.002