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. Author manuscript; available in PMC: 2017 Aug 1.
Published in final edited form as: Nature. 2017 Feb 1;542(7640):255–259. doi: 10.1038/nature21061

Extended Data Fig. 1.

Extended Data Fig. 1

Sequence alignment of domains I and II of separase. The secondary structure elements in the S. cerevisiae separase structure are shown and labeled. The boundaries of the domains are indicated. Residues in contact with securin are indicated with the purple dots. Sc: Saccharomyces cerevisiae, Zr: Zygosaccharomyces rouxii, Kl: Kluyveromyces lactis; Ag: Ashbya gossypii. Modified from an output from ESPript 36.