Figure 3.
Dendritic spine density. (a) Total dendritic spine density was unchanged among the three experimental groups (n.s.; p > 0.05). (b) One month after SCI, thin spine density decreased as compared with Sham (*p < 0.05). (c) In contrast following SCI, mushroom spine density increased as compared with Sham (*p < 0.05). ((b), (c)) Treatment with NSC23766 restored both thin and mushroom spine densities close-to-Sham levels (p > 0.05). As shown in (a), there was no effect of NSC23766 treatment on total spine density. Data are shown as mean ± SEM.