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. 2017 Jan 1;13:1744806916688016. doi: 10.1177/1744806916688016

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© The Author(s) 2017

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 4. — Spatial distribution of dendritic spines. (a) Thin and (b) mushroom spine densities increase significantly at regions closest to the soma after SCI as compared with Sham (*p < 0.05). ((b), (c)) Treatment with NSC23766 partially reduced these changes in thin and mushroom spines close-to-Sham levels. Moreover, NSC23766 treatment in SCI animals increased thin-shaped spines and decreased mushroom-shaped spines as compared with SCI animals and vehicle treatment only (#p < 0.05). As shown in (a), total spine densities do not change significantly at any dendritic region after SCI. Data are shown as mean ± SEM.