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. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: Respir Med. 2016 Dec 8;123:1–7. doi: 10.1016/j.rmed.2016.12.003

Table 3.

Prolonged QTc and lung function

Variable Odds ratio for prolonged QTc per 5-percentage point decrease in
percent predicted lung function
(95% CI)		 p-value
Men
FEV1% 1.10 (1.02 to 1.18) 0.01
FVC% 1.10 (1.01 to 1.21) 0.04
FEV1/FVC % 1.11 (1.00 to 1.24) 0.05
Women
FEV1% 1.08 (0.99 to 1.18) 0.09
FVC% 1.03 (0.92 to 1.15) 0.61
FEV1/FVC% 1.17 (1.02 to 1.34) 0.03

Prolonged QTc is defined as QTc Fram values of ≥460 ms in women and ≥450 ms in men.

All models are per 5-percentage-point decrease.

Models were adjusted for: age, sex, race, education, smoking status, pack-years, hypertension, diabetes, weight, height, and QT altering medications.