Table 4. Comparison of optimal Founder pairs with the AA combinations appearing for 5 subtype B pre-seroconverters with each of the clones sequenced.
Founder pairs | Env motifs connected | Patient: PSC35 | PSC89 | PSC24 | PSC73 | PSC182 | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Clone: 5 | 10 | 51 | 948 | 955 | 911 | 912 | 913 | 914 | 915 | 928 | 949 | |||
343–621 | QD | aNGS–aHR2 | DD | HE | QE | DD | ED | QE | QD | EY | IE | QE | HQ | KQ |
354–636 | PD | aNGS -HR2 | PS | PS | PS | PN | PS | PN | PD | PS | PS | PN | NS | GN |
553–624 | SN | HR1- NGS | SN | SD | S- | SE | SD | NE | SD | SG | SN | SD | SG | NN |
624–747 | ER | NGS—aNGS | NR | DR | -R | ER | DR | ER | DR | GR | NR | DR | GR | NR |
724–747 | RR | KenEpi- aNGS | PR | PR | PR | RR | PR | PR | PR | PR | PR | PR | QR | PR |
46–293 | RE | RR | RQ | RE | KE | KE | RK | RK | KE | KE | KA | RE | KE |