Table 1.
Hydrodynamic diameter (DH), and relaxivities (r) with 10% confidence intervals for select SPIONs and water-dispersible SPIONs measured at 7T.
| Nanoparticles | DH (nm) | r2 (mM−1·s−1) | r1 (mM−1·s−1) | r2* (mM−1·s−1) | r2/r1 |
|---|---|---|---|---|---|
| SPIONs-OA/PMe | 363 | 707 (663, 751) | 0.857 (0.771, 0.944) | 565 (525, 606) | 825 (728, 923) |
| SPIONs-OA/POH | 116 | 687 (496, 878) | 1.06 (0.959, 1.17) | 1280 (708, 1850) | 648 (458, 840) |
| SPIONs-PMe | 149 | 87(81, 93) | 0.159 (0.145, 0.173) | 358 (181, 534) | 546 (484, 608) |
| SPIONs-POH | 193 | 306 (270, 343) | 0.641 (0.529, 0.753) | 639 (566, 712) | 477 (377, 579) |
| Ferumoxides (Endorem®/Feridex®) | 120–180 | 132 | 1.8 | 111.9–134.3 * | 76.7 |
| Ferucarbotran A (Resovist, SHU55A) | 65 | 205 | 1.6 | - | 128.8 |