Table 1.

Studies of mesenchymal stem cells (MSCs) using quantitative proteomic techniques.

Proteomic Technique	MSC Source	Biological significance	Instrument	Ref.
2D-LC-MS/MS	Bone marrow	Characterization	Q-TOF	[10]
2DE-MALDI-TOF/TOF MS	Umbilical cord blood	Characterization	MALDI-TOF/TOF	[11]
2DE-MALDI-TOF-MS	Amniotic fluid	Characterization	MALDI-TOF	[12]
2D-LC-MALDI-MS	Bone marrow	Characterization	MALDI-TOF	[13]
2DE and combined MS and MS/MS	Bone marrow	Characterization	MALDI-TOF/TOF	[14]
2DE and combined MS and MS/MS	Umbilical cord	Characterization	MALDI-TOF/TOF	[14]
2DE and combined MS and MS/MS	Placenta	Characterization	MALDI-TOF/TOF	[14]
DIGE-MALDI-TOF/TOF	Bone marrow	Characterization	MALDI-TOF/TOF	[15]
2DE-PMF	Bone marrow	Characterization	MALDI-TOF/TOF	[16]
2DE-PMF	Bone marrow	Characterization	MALDI-TOF/TOF	[17]
GELFREE-LC-MALDI-TOF/TOF	Bone marrow	Characterization	MALDI-TOF/TOF	[18]
2DE-MALDI-TOF-MS	Bone marrow	Extension culture	MALDI-TOF	[19]
2DE-MALDI-TOF-MS	Bone marrow	Extension culture	MALDI-TOF	[20]
2DE-MALDI-TOF-MS/MS	Bone marrow	Extension culture	MALDI-TOF	[21]
2DE-MALDI-TOF-MS/MS	Bone marrow	Extension culture	MALDI-TOF	[22]
SELDI-TOF-MS	Adipose tissue	Extension culture	SELDI-TOF	[23]
2DE coupled MS	Bone marrow	Extension culture	Q-TOF	[24]
2DE-MALDI-MS	Bone marrow	Senescence	MALDI-TOF	[25]
2DE-ESI-Q-TOF-MS/MS	Bone marrow	Senescence	Q-TOF	[26]
DIGE-MALDI-TOF-MS	Bone marrow	Extension culture	MALDI-TOF	[27]
2DE-ESI-MS/MS	Bone marrow	Differentiation	Q-TOF	[28]
LC-MS/MS	Bone marrow	Differentiation	Q-TOF	[29]
DIGE-MALDI-TOF-MS	Bone marrow	Differentiation	MALDI-TOF	[30]
2DE-MALDI-TOF-MS	Bone marrow	Differentiation	MALDI-TOF	[31]
2DE-ESI-Q-TOF-MS/MS	Umbilical cord blood	Differentiation	Q-TOF	[32]
DIGE-MALDI-TOF/TOF-MS/MS	Adipose tissue	Differentiation	MALDI-TOF/TOF	[33]
2DE-MALDI-TOF/MS	Umbilical cord blood	Differentiation	MALDI-TOF	[34]
LC-coupled MS/MS	Intervertebral disc	Differentiation	LTQ	[35]
LC-coupled MS/MS	Bone marrow	Differentiation	LTQ-Orbitrap	[36]
DIGE- MALDI-TOF/TOF-MS/MS	Umbilical cord stroma	Differentiation	MALDI-TOF	[37]
SILAC-LC-MALDI-TOF/TOF-MS/MS	Bone marrow	Differentiation	MALDI-TOF/TOF	[38]
DIGE-MALDI-TOF-MS	Bone marrow	Differentiation	MALDI-TOF	[39]
SILAC-LC-MS/MS	Bone marrow	Differentiation	LTQ-Orbitrap	[40]
DIGE-IEF-MALDI-MS/MS	Bone marrow	Cell Therapy	MALDI-TOF/TOF	[41]
2DE-MALDI-TOF-MS	Bone marrow	Cell Therapy	MALDI-TOF	[42]
DIGE-MALDI-TOF/TOF-MS/MS	Bone marrow	Cell Therapy	MALDI-TOF/TOF	[43]
SDS-PAGE-LC coupled MS/MS	Bone marrow	Cell Therapy	LTQ	[44]
LC-coupled MS/MS	Bone marrow	Cell Therapy	LTQ-Orbitrap	[36]
DIGE-MALDI-TOF-MS	Bone marrow	Cell Therapy	MALDI-TOF	[45]

2DE, two-dimensional electrophoresis; MALDI, matrix-assisted laser desorption ionization; TOF, time of flight; PMF, peptide mass fingerprinting; DIGE, difference in-gel electrophoresis; SELDI, surface enhanced laser desorption/ionization; ESI, electrospray ionization; SILAC, stable isotope labeling by/with amino acids in cell culture; IEF, iso-electric focusing; SDS-PAGE, sodium dodecyl sulfate polyacrylamide gel electrophoresis; LTQ, linear trap quadrupole.