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. 2013 Sep 3;1(2):128–158. doi: 10.3390/proteomes1020128

Figure 6.

Figure 6

Quantitative analysis of immunoglobulins in milk. (a) Left panel: relative-abundance distribution of sIgM (IGHM and PIGR), sIgA (IGHA1, IGHA2 and PIGR) and IgG (IGHG1, IGHG2, IGHG3 and IGHG4). Right panel: significance p-values in hierarchical heat map; (b) Left panel: relative-abundance distribution of Ig classes of kappa and lambda. Right panel: significance p-values in hierarchical heat map of kappa and lambda chains and Ig variable-chain regions. HV, heavy chain variable region; KV, kappa chain variable region; LV, lambda chain variable region; IGKC, kappa chain constant region; IGLL, Ig lambda-like polypeptide; IGJ, Ig J chain. Color legends of heat maps are at log2 scale. Standard errors for each of IGHG1-4, IGHA1-2, IGHM, PIGR, IGLL and IGKC are available in Supplementary Figure S7.