Fig 3. Correlation between Δ Ki-67, H/A ratio and Ki-67 labeling index measured by the two methods.

(A, B) ΔKi-67 is moderately correlated with the Ki-67 labeling index (LI) based on the average method, and highly correlated with Ki-67 LI measured by the hot spot method (Pearson correlation coefficient, 0.535 and 0.731 respectively). (C, D) The H/A ratio is not correlated with Ki-67 LI measured by either method (Pearson correlation coefficients, -0.298 and -0.119, respectively).