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. 2017 Feb 10;12(2):e0172067. doi: 10.1371/journal.pone.0172067

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© 2017 Thompson et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 1 — (A) Immunohistochemistry of fibronectin expression in cav-1 +/+ and cav-1 -/- glands at low and high magnification. Results demonstrated an increased abundance fibronectin fibers surrounding the ducts and in the adipose stroma of cav-1 -/- glands. Fibronectin expression was also localized to the epithelial cells (red arrows) of the ducts in both cav-1 +/+ and cav-1 -/- glands. (B) The percent expression of fibronectin was significantly higher in cav-1 -/- glands compared to cav-1 +/+ glands. (C) The intensity of fibronectin staining was significantly higher in cav-1 -/- glands compared to cav-1 +/+ glands. Scale bars are 50 μM and 20 μM in low and high magnification images, respectively. *p≤0.05. Fn: fibronectin. Results are reported as the mean ± the SEM.