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. 2016 Aug 10;7(35):56060–56070. doi: 10.18632/oncotarget.11180

Figure 2. Efffect of C5a overexpression on atherosclerotic lesions in ApoE−/− mice after a 12-week high-fat diet.

Figure 2

A., Quantitative analysis of atherosclerotic lesions by en face staining after C5a receptor antagonist treatment. B. and C., Quantitative analysis of atherosclerotic lesions by en face staining (B) and in aortic roots (C) after a high fat diet for 8 weeks. D. and E., Representative photomicrographs showing atherosclerotic lesions on the surface of aorta (en face staining, D) and aortic roots (E). F. and G. Quantitative analysis of atherosclerotic lesions by en face staining (G) and in aortic roots (F). Data are mean±SEM in 6 sections for each mouse sample. N = 12 per group. *P < 0.05, **P < 0.01.