Figure 2. Combined treatment of DHA and/or PE with TMZ as well as TMZ-monotherapy show a massive reduction of invasiveness in orthotopically implanted T269 derived tumors in mice.

Tumor cells are stained with anti-human nestin antibody and appear in brown. The invasive pattern of the six treatment groups (control, PE only, TMZ, TMZ + PE, TMZ + DHA, TMZ + DHA + PE) are compared with the help of one overview image, and higher magnified images of the ipsilateral, corpus callosum- and contralateral regions.