Table 1. Effects of MNKI-8e on cell viability.
Cell lines | FAB subtype | GI50 (μM)* |
---|---|---|
MV4-11 | M5 | 1.32 ± 0.40 |
Kasumi-1 | M2 | 7.36 ± 1.16 |
PL-21 | M3 | 7.12 ± 2.15 |
KG-1 | M0/M1 | 1.23 ± 0.22 |
U937 | M5 | 3.14 ± 0.30 |
WI-38** | >100** |
By 72 h resazurin assay, and
72 h MTT assay. Data given are the mean ± SD from at least two replicates