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. 2016 Jul 27;7(35):56842–56854. doi: 10.18632/oncotarget.10863

Figure 4. The in vivo effect of CYD 6-17 on tumor growth.

Figure 4

A. Effect of CYD 6-17 on the volume of TCC tumors. When the tumors became palpable, animals (n = 9 for each group) were randomized for CYD6-17 treatment. Tumor volume was measured every other day (Upper panel). All tumors were excised at Day 12 and photographed (Lower panel). B. Effect of CYD 6-17 on the weight of TCC tumors. *Significant difference between control and CYD 6-17 treatment group (p< 0.05). Error bars represent SD. C. Histologic analyses (200×) of TCC tumors after CYD6-17 treatment. Upper panel: H&E. Lower panel: IHC of cleaved Caspase-3. D. Effect of CYD 6-17 on apoptosis markers in tumors.