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. 2016 Jul 29;7(35):56944–56957. doi: 10.18632/oncotarget.10922

Figure 2. HBx induces IGF-II mRNA and protein expression.

Figure 2

A. and C. Relative mRNA expression of IGF-II in WT and HBx mouse livers (A) Mean ± SD; * P< 0.05, ** P< 0.01, n=3, HepG2-Mock and HepG2-HBx cells (C) Mean + SD; * P< 0.05, n=5-8. B. Immunohistochemistry images of 3-week-old WT and HBx-mouse livers stained with IGF-II. Original magnifications 40X. Data are representative of 3-5 mice per group. D. Secreted IGF-II protein levels from HepG2-Mock and HBx cells were measured. Mean ± SD; * P< 0.05, n=6.