Table 4. Multivariate model including clinical, biological and genetic characteristics of CMML patients at diagnosis (n=56).

Overall survival				Progression free survival
Variable	HR	95% CI	P	Variable	HR	95% CI	P
CPSSa:	1.2	0.4 to 3.4	0.005	CPSSa:	2.7	0.8 to 8.7	0.002
Int-1	6.2	2.0 to 18.8	0.695	Int-1	16.5	3.4 to 79.4	0.093
Int-2			0.001	Int-2			<0.001
Presence of adverse risk gene mutationsb,c	2.9	1.0 to 8.2	0.042	TET2 wtd	4.1	1.3 to 12.8	0.013

^aReference category: Low risk

^bASXL1, EZH2, NRAS, SRSF2

^cReference category: No mutations

^dReference category: TET2 mutation

CI: confidence interval