Skip to main content
. 2016 Aug 1;7(35):57086–57098. doi: 10.18632/oncotarget.10977

Figure 6. p66Shc affects STAT4 protein stability.

Figure 6

A. qRT-PCR analysis of STAT4 and p66shc mRNA in EBV-B cells transfected with siRNA targeting p66shc. The relative abundance of the genes transcripts as described above and is expressed as the normalized fold expression (mean±SD, (n≥3). B. Immunoblot analysis of STAT4 and the three Shc isoforms in EBV-B cells transfected with a siRNA targeting p66shc. Filters were reprobed for actin as loading control. The histogram shows the quantification of the levels of STAT4, normalized to actin (n≥3). ***P≤0.001; and **P<0.01.