Skip to main content
. 2016 Aug 9;7(35):57213–57227. doi: 10.18632/oncotarget.11127

Figure 5. Effects of celecoxib and sulindac on transforming growth factor (TGF)-β1-induced A549 cell invasion.

Figure 5

A. For the electric cell-substrate impedance sensing invasion assay, resistance changes in the impedance at 4 kHz as confluent layers of HUVEC cells were challenged with A549 cells suspensions. The control curve of HUVEC cells received media without A549 cells. A549 cells were treated as above and changes in resistance were monitored for 40 h. The data represent the mean ± SD of three independent experiments. *p < 0.05 compared with the control (HUVEC + A549), **p < 0.05 compared to the HUVEC + A549 + TGF-β1 group. B. Effect of celecoxib and sulindac on A549 cell invasion in a 200× light microscope after crystal violet staining by matrigel invasion assay as described in Materials and Methods. Matrigel invasion of A549 cells counted in five random views. The data represent the mean ± SD of three independent experiments. *p < 0.01 compared with the control, ** p < 0.05 compared to the TGF-β1 group.