Table 1.
Cell-bound activity per cell (Bq/cell) required for a 50% (A50) and 90% (A10) reduction in viability and clonogenicity in DU145 cells compared to untreated cells (determined by interpolation of data in Figs. 4A and 5A).
| A50 (Bq/cell) |
A10 (Bq/cell) |
|||
|---|---|---|---|---|
| 67Ga-oxine | 111In-oxine | 67Ga-oxine | 111In-oxine | |
| Viability (Trypan blue) | 1.0 | 1.0 | 1.5 | N/A |
| Clonogenic | 0.3 | 0.7 | 1.0 | 0.9 |
No A10 value exists for 111In-oxine (viability assay), as loss of membrane integrity was not achieved in more than 75% of cells.