Table 6. The function and pathway enrichment of DEGs of black module and pink module.
| ID | Terms | FDR | Genes |
|---|---|---|---|
| Black module-biological process | |||
| GO:0007586 | Digestion | 4.66E-05 | SSTR1, BAAT, SCTR |
| GO:0006811 | Ion transport | 0.00158761 | KCNK17, SCN1A, CFTR, SLC5A9 |
| GO:0055085 | Transmembrane transport | 0.00176614 | SCN1A, SLC46A2, CFTR, SLC5A9 |
| GO:0007165 | Signal transduction | 0.00987753 | RASGRF1, NRGN, IGFALS, RRAD |
| Black module-cellular component | |||
| GO:0005576 | Extracellular region | 3.96E-06 | C16orf89, SCGB3A2, HP, SFTPD, FIGF, WFDC2, SCGB3A1, IGFAL |
| GO:0005615 | Extracellular space | 3.72E-05 | SFTPD, FIGF, WFDC2, SCGB3A1,IGFALS,BMP3 |
| GO:0005886 | Plasma membrane | 0.000342 | RASGRF1, SSTR1, KCNK17, SCN1A, SCTR, SLC46A2, CLDN2, LRP2, RRAD |
| GO:0016021 | Integral to membrane | 0.013611 | KLHDC7A, KCNK17, SCN1A, SLC46A2, CLDN2, LRP2, CFTR, SLC5A9 |
| GO:0016020 | Membrane | 0.023071 | KLHDC7A, KCNK17, SCN1A, FIGF, LRP2, CFTR, SLC5A |
| Black-KEGG pathway | |||
| hsa04976 | Bile secretion | 1.91E-05 | CFTR, SCTR, BAAT |
| Pink-biological process | |||
| GO:0035085 | Cilium axoneme | 2.38E-06 | TEKT3, DNAH6, TEKT2 |
| GO:0005929 | Cilium | 1.34E-06 | SNTN, TEKT3, DNAH6, TEKT2 |
| GO:0005737 | Cytoplasm | 1.31E-05 | TEKT3, DNAH6, TEKT2, DYNLRB2 |
| GO:0005856 | Cytoskeleton | 1.31E-05 | TEKT3, DNAH6, TEKT2, DYNLRB2 |
| GO:0005874 | Microtubule | 1.31E-05 | TEKT3, DNAH6, TEKT2, DYNLRB2 |
FDR, false discovery rate; DEG, differentially expressed genes.