Table 3. Sequentially recorded variables of the 145 patients in the first 24 postoperative hours according to ICU length of stay.
Variable | ICU LOS | Time elapsed after ICU admission (hours) | Interaction P value | |||
---|---|---|---|---|---|---|
0–1 | 1–4 | 4–12 | 12–24 | |||
Temperature, °C | N | 36.2±0.7 | 36.8±0.8* | 37.6±0.7† | 37.4±0.5 | 0.009 |
P | 36.1±0.8 | 36.5±0.9* | 37.3±0.7† | 37.3±0.6 | ||
HR, beats/min | N | 86±13 | 86±15 | 88±13 | 87±12 | 0.4 |
P | 87±15 | 88±16 | 89±13 | 90±13 | ||
SAP, mmHg | N | 123±14 | 118±15 | 120±14 | 126±13 | 0.254 |
P | 121±18 | 119±17 | 117±13 | 124±17 | ||
DAP, mmHg | N | 65±10* | 62±9 | 62±7 | 65±7† | 0.008 |
P | 61±9* | 60±9 | 61±9 | 61±9† | ||
MAP, mmHg | N | 84±11* | 80±11 | 81±8 | 84±8* | 0.024 |
P | 80±11* | 79±10 | 79±10 | 80±11* | ||
CVP, mmHg | N | 14±3 | 14±3 | 14±3* | 13±3 | 0.432 |
P | 14±4 | 16±4 | 15±4* | 15±5 | ||
Blood gases | ||||||
pH | N | 7.42±0.05 | 7.44±0.05 | 7.41±0.04 | 7.40±0.03 | 0.365 |
P | 7.41±0.05 | 7.42±0.06 | 7.41±0.05 | 7.41±0.05 | ||
PaO2, mmHg | N | 285±105 | 186±43† | 147±35* | 117±27 | 0.039 |
P | 269±108 | 164±48† | 135±34* | 111±30 | ||
PaCO2, mmHg | N | 35.1±4.7 | 33.6±4.7* | 36.0±4.9 | 37.5±4.1 | 0.105 |
P | 36.7±5.8 | 35.3±4.8* | 35.7±4.7 | 37.9±5.3 | ||
HCO3−, mmol/L | N | 22.8±1.2 | 22.7±1.2 | 22.6±1.5 | 23.1±1.6 | 0.301 |
P | 23.0±1.8 | 23.1±2.28 | 22.8±2.6 | 23.4±2.6 | ||
SaO2, % | N | 99.6±0.4 | 99.2±0.6* | 98.8±0.9 | 98.1±1.3 | 0.041 |
P | 99.4±0.5 | 98.9±0.8* | 98.7±0.9 | 97.8±1.7 | ||
PcvO2, mmHg | N | 36.9±6.1 | 34.5±4.2 | 37.2±5.2 | 35.9±4.7 | 0.779 |
P | 39.1±14.3 | 34.5±5.1 | 35.6±5.8 | 36.1±4.4 | ||
ScvO2, % | N | 67.8±9.9 | 63.6±7.2 | 66.6±7.9 | 65.0±7.8 | 0.335 |
P | 70.5±8.1 | 64.4±8.1 | 65.8±9.1 | 66.0±7.1 | ||
PcvCO2, mmHg | N | 41.3±5.2 | 42.6±6.1 | 44.0±5.2 | 44.4±4.4 | 0.504 |
P | 42.7±6.3 | 43.2±5.6 | 43.0±5.5 | 45.2±5.6 | ||
Lactate, mmol/L | N | 1.89±0.84* | 1.69±0.93 | 1.55±0.76* | 1.49±0.70† | 0.008 |
P | 2.38±1.81* | 2.18±2.05 | 2.29±2.41* | 1.97±1.17† | ||
Hb, g/dL | N | 10.09±1.12 | 10.39±1.01* | 10.89±1.00† | 11.18±0.86* | 0.009 |
P | 9.88±1.26 | 10.02±1.14* | 10.36±1.09† | 10.78±1.15* | ||
Glucose, mg/dL | N | 147±27* | 141±28ǂ | 167±33* | 168±29* | 0.001 |
P | 163±43* | 163±43ǂ | 182±41* | 182±36* | ||
PaO2/FiO2, mmHg | N | 336±114* | 358±98† | 333±85ǂ | 359±92ǂ | <0.001 |
P | 292±103* | 304±85† | 277±80ǂ | 259±100ǂ | ||
D(A-a)O2, mmHg | N | 288±113* | 149±67 | 129±57ǂ | 75±57ǂ | <0.001 |
P | 340±110* | 183±70 | 178±69ǂ | 170±89ǂ | ||
P(cv-a)CO2, mmHg | N | 6.26±4.82 | 9.16±3.78 | 7.84±4.30 | 6.97±3.15 | 0.501 |
P | 6.03±5.87 | 8.15±3.79 | 7.53±3.69 | 7.32±3.47 | ||
CaO2, mL/dL | N | 14.56±1.51 | 14.59±1.37* | 15.09±1.33† | 15.29±1.24* | 0.003 |
P | 14.20±1.66 | 13.99±1.57* | 14.33±1.46† | 14.70±1.60* | ||
CcvO2, mL/dL | N | 9.42±1.70 | 9.08±1.25 | 9.98±1.50* | 10.02±1.56 | 0.24 |
P | 9.60±1.60 | 8.90±1.57 | 9.40±1.73* | 9.82±1.62 | ||
C(a-cv)O2, mL/dL | N | 5.13±1.40* | 5.51±1.23* | 5.11±1.29 | 5.27±1.11* | 0.005 |
P | 4.60±1.26* | 5.09±1.15* | 4.93±1.32 | 4.86±1.00* |
Values are mean ± SD. *, P<0.05 for differences between groups; †, P<0.01 for differences between groups; ǂ, P<0.001 for differences between groups. ICU, intensive care unit; LOS, length of stay; N, normal; P, prolonged; HR, heart rate; SAP, systolic arterial blood pressure; MAP, mean arterial blood pressure; DAP, diastolic arterial blood pressure; CVP, central venous pressure; PaO2, partial pressure of arterial oxygen; PaCO2, partial pressure of arterial carbon dioxide; HCO3−, bicarbonate; SaO2, hemoglobin oxygen saturation of arterial blood; PcvO2, partial pressure of central venous oxygen; ScvO2, hemoglobin oxygen saturation in central venous blood; PcvCO2, partial pressure of central venous carbon dioxide; Hb, hemoglobin; PaO2/FiO2, ratio of arterial oxygen partial pressure to inspired oxygen fraction; D(A-a)O2, alveolar-arterial oxygen gradient; P(cv-a)CO2, central venous to arterial carbon dioxide partial pressure difference; CaO2, arterial oxygen content; CcvO2, central venous oxygen content; C(a-cv)O2, arteriovenous oxygen content difference.