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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: Cell Microbiol. 2016 Oct 11;19(3):10.1111/cmi.12668. doi: 10.1111/cmi.12668

Figure 4. Differential actin filament dynamics during migration of macrophages infected with L. amazonensis.

Figure 4

BMDM from Lifeact mice were infected or not (control) with L. amazonensis axenic amastigotes for 1h. BMDM were then washed to remove extracellular parasites, cultured at 34°C for another 24 h, followed by fluorescence time-lapse image acquisition for 26.7 min. Arrowheads: F-actin (green) dynamics at ruffling leading edges of macrophages. Arrows: infected macrophages showing altered F-actin propagating waves at cell boundaries. Bars: 10 μm. See supplemental videos.