Table 2.

Predictors of the infant gut microbiome at age 3–6 months (n=325)

		Overall Diversity (Shannon Diversity Index)
		Univariate Associations		Multiple Regression Model
		Beta	(P value)	Beta	(P value)	Model adj. R2
Child’s Race*						26%
Hispanic		−0.232	0.003	−0.09	0.26
Caucasian		−0.351	<0.0001	−0.15	0.02
Other		−0.258	0.004	−0.10	0.18
Breast Fed exclusively**		−0.531	<0.0001	−0.45	<0.001
Breast Fed supplemented with formula**		−0.185	0.0005	−0.13	0.02
Solid Foods Introduced (Y/N)		0.127	0.02	0.11	0.04
C-section (Y/N)		0.146	0.006	0.11	0.04
Maternal Abx labor (Y/N)		0.105	0.04	0.008	0.85
Age at Fecal Sampling (weeks)		0.013	0.02	0.009	0.11
Maternal BMI at first Ob visit		0.012	0.0009	0.006	0.10
Pet dog (Y/N)		−0.140	0.01	−0.03	0.50
Pet cat (Y/N)		−0.153	0.04	−0.05	0.54
Child Abx in first days of life (Y/N)		0.078	0.40
Treatment Group		0.026	0.61
Smoking During Pregnancy (Y/N)		0.162	0.39
Gestational Diabetes (Y/N)		0.205	0.14
Gestational Age (weeks)		−0.02	0.08
Female (vs. Male)		−0.018	0.73
Day care attendance (Y/N)		0.021	0.76
Mold/Mildew on walls (Y/N)		−0.087	0.39
Water damage in home (Y/N)		−0.086	0.39
Cord Blood Vitamin D level (ng/ml)		−0.004	0.06

^*African American Race/ethnicity used as reference

^**Breastfeeding data from first 6 months of life; comparison group is exclusively formula fed; For all models, beta coefficients and p value bolded if p<0.05