Table 3.

Infant Predictors of Bacterial Co-abundance Factor Scores (Linear Regression Results, n=325)

		Multiple Regression Models for Bacterial Co-Abundance Groupings
Dominant Phyla for Grouping Dominant Genera		Firmicutes Lachnospiraceae (+) Clostridales U. (+) Factor 1 Score		Proteobacteria Klebsiella (+) Enterobacter (+) Factor 2 Score		Bacteroidetes Bacteroides (+) Shigella (−) Bifidobacterium (−) Factor 3 Score		Firmicutes Veillonella (+) Clostridium (+) Factor 4 Score
Infant Characteristics:		Beta	(P value)	Beta	(P value)	Beta	(P value)	Beta	(P value)
Gestational Age (weeks)		−0.03	0.43	−0.02	0.37	0.001	0.97	−0.02	0.37
Child’s Race
Hispanic		0.06	0.70	−0.23	0.09	0.07	0.69	0.54	0.003
Caucasian		0.08	0.56	−0.14	0.20	0.29	0.05	0.42	0.002
Other		0.10	0.47	0.05	0.64	−0.05	0.78	0.31	0.04
Male (vs. Female)		−0.31	0.002	0.04	0.62	0.06	0.55	0.02	0.96
Breast Fed exclusively**		−0.85	<0.001	−0.27	0.02	−0.23	0.17	0.22	0.07
Breast Fed supplemented with formula**		−0.28	0.02	0.01	0.90	0.01	0.83	0.08	0.50
Solid Foods Introduced (Y/N)		0.08	0.47	0.15	0.13	0.23	0.07	−0.003	0.90
C-section (Y/N)		0.27	0.02	0.09	0.33	−0.29	0.01	0.14	0.05
Maternal Abx labor (Y/N)		0.19	0.07	−0.04	0.64	−0.22	0.04	−0.006	0.71
Infant Abx, 1st days life (Y/N)		−0.02	0.95	−0.05	0.80	0.18	0.42	−0.35	0.06
Age at fecal flora sampling (weeks)		0.01	0.34	−0.02	0.06	−0.009	0.48	0.004	0.71
Dog Ownership (Y/N)		−0.01	0.91	−0.14	0.16	−0.03	0.80	−0.09	0.40
Cat Ownership (Y/N)		0.29	0.07	−0.21	0.11	0.50	0.003	−0.31	0.03
Daycare Attendance (Y/N)		−0.02	0.91	−0.12	0.31	0.02	0.90	0.13	0.31
Maternal BMI		0.003	0.69	−0.006	0.26	−0.002	0.74	0.004	0.56

Beta and p values bolded if p<0.05

^*African American Race/ethnic group as the reference category;

^**Breastfeeding data from first 6 months of life; reference group is exclusively formula fed