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. 2017 Feb 10;18:150. doi: 10.1186/s12864-017-3527-7

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© The Author(s) 2017

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License(http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Epigenome-wide association study in a Qatari family study. Comparison of the results obtained in the Epigenome-wide association studies when the relatedness between subjects was evaluated using the family structures and when it was inferred from genome-wide SNPs by means of GCTA [11]. Left panel effect size estimates for the association between CpG methylation status and BMI. Right panel estimated genetic ( $σ_{a}^{2}$ , in blue) and environmental ( $σ_{e}^{2}$ , in red) variances