Table 1.
Clinical and demographic characteristics of OCD patients and HCs
| OCD patients (n = 40) | HCs (n = 40) | P value | |
|---|---|---|---|
| Age (years, mean ± SD)a | 35.40 ± 12.07 | 39.70 ± 12.97 | 0.129 |
| Gender (female/male)b | 20/20 | 26/14 | 0.175 |
| Handedness (right/left)b | 37/3 | 39/1 | 0.305 |
| Education (years, mean ± SD)a | 13.69 ± 2.43 | 15.15 ± 1.35 | 0.001 |
| Illness duration (years, mean ± SD) | 11.33 ± 10.10 | ||
| Age of onset (years, mean ± SD) | 23.98 ± 11.24 | ||
| Total Y-BOCS (total score, mean ± SD) | 21.95 ± 6.32 | ||
| HDRS (17 items)a | 6.08 ± 6.87 | 0.55 ± 0.88 | 0.000 |
| 5-HTTLPRa | |||
| 14/14 | 26 | 17 | 0.040 |
| 14/16 | 13 | 22 | |
| 16/16 | 1 | 1 | |
| LA allele carriers (SLA, LALG, LALA)b | 10 | 20 | 0.021 |
| Non-LA allele carriers (SS, SLG, LGLG)b | 30 | 20 |
We found a significant difference between the OCD patients and HCs in the distribution of LA allele carriers or non-LA allele carriers of 5-HTTLPR polymorphism
a T test
bChi square test