Table 1.
Patient demographic and clinical characteristics
| RA n = 50 | Controls n = 39 | |
|---|---|---|
| Age (yrs) | 55.4 ± 12.8 | 52.1 ± 11.4 |
| Gender-Female | 35 (70%) | 27 (69%) |
| Race- | ||
| Pacific Islander | 1 (2%) | 0 (0%) |
| African American | 14 (28%) | 12 (31%) |
| Caucasian | 35 (70%) | 27 (69%) |
| Body mass index (kg/m2) | 30.5 ± 7.5 | 29.0 ± 5.3 |
| Waist circumference (cm) | 95.3 ± 16.7 | 92.1 ± 13.3 |
| Disability (HAQ-DI) | 0.7 ± 0.7 | 0 ± 0 |
| Disease Activity (DAS-28) | 3.0 ± 1.4 | n/a |
| hsCRP (mg/L) | 3.8 ± 4.8† | 2.0 ± 2.8 |
| Basal activity (% min/week) | 91.2 ± 6.0 | 88.8 ± 6.1 |
| Exercise (% min/week) | 1.1 ± 1.5 | 1.5 ± 1.3 |
| Total cholesterol (mg/dl) | 176.6 ± 30.7† | 185.9 ± 32.3 |
| LDL-cholesterol (mg/dl) | 105.0 ± 24.7† | 117.2 ± 26.4 |
| HDL-cholesterol (mg/dl) | 53.7 ± 1.3 | 49.2 ± 1.3 |
| Triglycerides (mg/dl) | 93.6 ± 1.6 | 96.6 ± 1.5 |
| LDL Particles – Total (nmol/L) | 965.1 ± 1.3† | 1117.6 ± 1.4 |
| Large LDL Particles (nmol/L) | 363.0 ± 1.8 | 363.1 ± 1.6 |
| Small LDL Particles (nmol/L) | 386.2 ± 2.1† | 521.2 ± 2.0 |
| LDL Particle Size (nm) | 20.9 ± 1.0† | 20.7 ± 1.0 |
| HDL Particles – Total (μmol/L) | 29.1 ± 1.2 | 29.3 ± 1.2 |
| Large HDL Particles (μmol/L) | 4.9 ± 1.8 | 3.9 ± 1.9 |
| Medium HDL Particles (μmol/L) | 8.5 ± 1.6 | 8.8 ± 1.9 |
| Small HDL Particles (μmol/L) | 13.8 ± 1.4 | 13.9 ± 1.5 |
| HDL Particle Size (nm) | 9.3 ± 1.1† | 9.0 ± 1.1 |
Data are presented as mean ± SD, geometric mean ± SD for nonnormally distributed variables, or frequency (percent)
†Significantly different (P < 0.05) as compared to controls using mixed models
HAQ-DI Health Assessment Questionnaire Disability Index, DAS ESR -28 Disease activity score with 28 joint count using erythrocyte sedimentation rate, hsCRP High sensitivity C-reactive protein, LDL Low density lipoprotein, HDL High density lipoprotein, RA Rheumatoid arthritis