Table 2.
Levels of serum TGF-β1 and TGF-β3 in mice after ConA injection.
| (n) | TGF-β1 (pg/mL) | TGF-β3 (pg/mL) | TGF-β3/β1 ratio | |
|---|---|---|---|---|
| Control | 8 | 21.12 ± 4.01 | 10.56 ± 6.79 | 0.45 ± 0.12 |
| 2 h | 7 | 25.34 ± 6.32 | 14.32 ± 8.92 | 0.53 ± 0.23 |
| 8 h | 5 | 36.43 ± 9.67∗ | 25.34 ± 6.45# | 0.69 ± 0.09 |
| 24 h | 7 | 28.77 ± 8.44∗ | 18.37 ± 11.25# | 0.62 ± 0.18 |
| 48 h | 8 | 25.79 ± 9.24 | 9.26 ± 3.14 | 0.35 ± 0.06∗# |
∗8 h and 24 h after ConA injection, serum concentrations of TGF-β1 were significantly higher than the control group (P = 0.031 and 0.046, resp.); peak time was 8 h.
#After ConA injection, on 8 h and 24 h, concentration of TGF-β3 was also significantly higher than the control group (P = 0.025 and 0.043, resp.); peak time was 8 h.
∗#After ConA injection, the ratio of TGF-β3/TGF-β1 decreased significantly at 48 h compared with control group (P = 0.046).