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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: Anal Bioanal Chem. 2016 Dec 16;409(7):1749–1763. doi: 10.1007/s00216-016-0125-5

Figure 5.

Figure 5

Network analysis of significant corrected phosphosites. Protein-expression corrected phosphosites that met significance criteria were compared against the STRING protein-protein interaction database. “High confidence” interactions are shown. The color of each node indicates the magnitude and direction of the SW620/SW480 fold change. Background colors highlight relationships observed among clusters: gray for mitosis-related phosphoproteins, yellow for cell-cell contacts and cytoskeleton-related clusters, and green for mRNA biogenesis-related clusters. EIF4ENIF1 (4E-T) and DCP1A, shown as diamonds, had missing protein-level information but had GO annotations that associated them with the mRNA – lifecycle-related clusters.