Table 1. Quantification of ribbon synapses.
Synapses were counted in IHCs of 2 organs of Corti of wild-type and 2 organs of Corti of sirtaki mice (for each genotype 82 IHCs were analyzed). Intact synapses were defined by the juxtaposition of pairs of pre- and postsynaptic fluorescent spots. The number of GluA receptors per cell includes the GluA receptors with and those without the presynaptic ribbon partner. The same applies to the number of ribbons given in the table. Data are shown as mean ± S.E.M., paired t-test.
No. of synapses/cell | No. of ribbons/cell | No. of GluA/cell | ||||
---|---|---|---|---|---|---|
sirtaki | 11.5 ± 0.6 | p = 0.2 | 12.2 ± 0.5 | p = 0.049 | 12.6 ± 0.1 | p = 0.002 |
wild-type | 12.7 ± 0.7 | 15.0 ± 0.8 | 14.2 ± 0.0 |