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. Author manuscript; available in PMC: 2018 Mar 6.
Published in final edited form as: Neuroscience. 2017 Jan 3;344:276–292. doi: 10.1016/j.neuroscience.2016.12.041

Figure 3.

Figure 3

Effects of ibuprofen on NMDA receptor mRNA expression in superficial lateral frontal cortex. mRNA densities (fmole 33P-dATP/mm2) for all GluN2B (A) and GluN1 (GluN1-pan; B) subunits and for 3 splice forms of the GluN1 subunit, GluN1-1 (C), GluN1-2 (D), and GluN1-3 (E) in the superficial layers (II-III) of the lateral frontal cortex for different ages and treatments. Ibuprofen reduced mRNA expression of GluN2B (A), GluN1-pan (B), and GluN1-1 (C), but increased GluN1-3 mRNA (E) in superficial lateral frontal cortex, with data collapsed across ages (main effect of treatment (p<.05)). Mean ± SEM, N = 5-6.