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. Author manuscript; available in PMC: 2018 Feb 15.
Published in final edited form as: Dev Biol. 2017 Jan 6;422(2):135–145. doi: 10.1016/j.ydbio.2016.12.025

Figure 2. Polarity defects in pam-1 mutants are not caused by increased centrosome-cortical distance.

Figure 2

A) Centrosomes in both WT and pam-1 mutant embryos (arrowhead; γ-tub::GFP) appear near the cortex at the same relative distance and in most cases cue symmetry breaking (*). Posterior is to the right in all images. B) While initial centrosome distance correlates with increased time to symmetry breaking in WT embryos (n=23), this trend is not significant in pam-1 mutant embryos (n=36). C) When distance from the cortex is plotted against the extent of PAR-1 localization at NEBD, we see no correlation (WT n=23, pam-1 n=21). Each dot represents one embryo.