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. Author manuscript; available in PMC: 2018 Feb 15.
Published in final edited form as: Neuroimage. 2016 Dec 13;147:262–271. doi: 10.1016/j.neuroimage.2016.12.022

Figure 5. Differential aging of positive modulation and negative modulation regions.

Figure 5

Age-related decreases in difficulty modulation in the positive modulation network (i.e., right fronto-parietal cortices) were not evident until between middle and older age (Panel A). Age-related differences in the negative modulation network (i.e., ventromedial prefrontal, precuneus/posterior cingulate, left angular and middle frontal gyri) occurred earlier in the lifespan, between younger and middle-age (Panel B). Error bars indicate standard error of the mean.