Table 1.
Fold changes in transcript abundance of chromatin-modifying enzymes at 3 days
| Gene Group | Genes | 3d |
|---|---|---|
| DHD | Kdm1a | 2.00 (0.22) |
| DM | Dnmt1 | 5.24 (0.26) |
| Dnmt3b | 2.46 (0.56) | |
| HA | Ciita | 2.49 (0.25) |
| Csrp2bp | 2.12 (0.23) | |
| Esco2 | 26.51 (3.07) | |
| Hat1 | 3.31 (0.19) | |
| Kat2a | 3.10 (0.42) | |
| Kat2b | 0.57 (0.02) | |
| Kat7 | 1.74 (0.11) | |
| HD | Hdac1 | 2.25 (0.14) |
| Hdac11 | 0.27 (0.02) | |
| Hdac2 | 2.03 (0.18) | |
| Hdac3 | 1.95 (0.12) | |
| Hdac6 | 1.92 (0.16) | |
| HM | Carm1 | 2.61 (0.34) |
| Prmt1 | 3.81 (0.45) | |
| Prmt3 | 2.90 (0.06) | |
| Prmt5 | 2.69 (0.17) | |
| Prmt6 | 2.09 (0.30) | |
| Prmt7 | 2.08 (0.25) | |
| Setdb2 | 2.08 (0.24) | |
| Smyd1 | 0.36 (0.09) | |
| Suv39h1 | 3.57 (0.40) | |
| HP | Aurka | 33.57 (1.17) |
| Aurkb | 61.26 (2.30) | |
| Nek6 | 3.34 (0.29) | |
| Pak1 | 10.13 (0.84) | |
| HU | Dzip3 | 2.63 (0.22) |
| Rnf20 | 2.01 (0.10) | |
| Ube2a | 1.98 (0.17) | |
| Usp16 | 2.11 (0.28) | |
| Usp22 | 1.82 (0.31) | |
| SET | Setd1a | 1.60 (0.13) |
| Setd4 | 1.80 (0.31) | |
| Setd8 | 2.52 (0.31) | |
| Whsc1 | 5.03 (0.89) | |
All expression changes (average (standard deviation)) shown are significant (p<0.05) relative to un-injured levels.
Groups: DHD (DNA/Histone Demethylases), DM (DNA Methyltransferases), HA (Histone Acetyltransferases), HD (Histone Deacetylases), HM (Histone Methyltransferases), HP (Histone Phosphorylation), HU (Histone Ubiquitination), SET (SET Domain Proteins; Histone Methyltransferase Activity)