Table 3.
Methylation of CpG sites of DNA in murine tendon for each experimental group
| Group | Genome-Wide | Non-Coding | Intron | Exon | Promoter | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| CpG I | Other | CpG I | Other | CpG I | Other | CpG I | Other | CpG I | Other | |
| 3d | 27 | 1058 | 6 | 539 | 9 | 412 | 13 | 99 | 4 | 31 |
| 14d | 9 | 622 | 0 | 347 | 4 | 232 | 5 | 29 | 0 | 26 |
| 28d | 17 | 620 | 0 | 338 | 4 | 230 | 14 | 47 | 9 | 23 |
| 14dTM | 19 | 693 | 1 | 357 | 2 | 280 | 15 | 45 | 4 | 26 |
| 28dTM | 17 | 609 | 0 | 333 | 2 | 230 | 11 | 37 | 5 | 27 |
All sites exhibited greater than 80% differential methylation compared to the same sites in un-injured tendons. Location of CpG sites (non-coding, intron, exon, and promoter) was determined using the UCSC database refseq gene track