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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Adv Drug Deliv Rev. 2016 Aug 12;116:63–72. doi: 10.1016/j.addr.2016.08.002

Figure 2.

Figure 2

Highlighted transport processes within the human placental barrier. It should be noted that this does not represent an exhaustive list of transporters present in the placental trophoblast or fetal capillary endothelium. Trophoblast cells represent the rate-limiting barrier separating maternal and fetal circulations within the placenta. MDR1, multidrug resistance protein 1 (P-glycoprotein); BCRP, breast cancer resistance protein; MRP2, multidrug resistance-associated protein 2; OATP4A1, organic anion transporting polypeptide 4A1; OCTN1, novel organic cation transporter 1; OCTN2, novel organic cation transporter 2; MATE1, multidrug and toxin extruding protein 1; MRP1, multidrug resistance-associated protein 1; OAT4, organic anion transporter 4; OATP2B1, organic anion transporting polypeptide 2B1; OCT1, organic cation transporter 1; OCT3, organic cation transporter 3. Question marks indicate transport processes requiring further characterization.