Table 1.
Point mutations in the rpoB gene of Bacillus velezensis that confer Rifr.
| Strain | Nucleotide | Amino acid | Rifr | Number∗ |
|---|---|---|---|---|
| CC09 | NA | NA | - | NA |
| CC09-RIF1 | C1453T | H485Y | + | 2 |
| CC09-RIF5 | C1469T | S490L | + | 2 |
| CC09-RIF2 | CA1453(4) TG | H485C | + | 2 |
| CC09-RIF3 | A1454G | H485R | + | 4 |
| CC09-RIF4 | C1453G | H485D | + | 1 |
| CC09-RIF6 | A1415G | Q472R | + | 2 |
| CC09-RIF7 | C1469T/C1850T | S490L/S617F | + | 1 |
| CC09-6I7F | C1850T | S617F | - | NA |
∗Number of spontaneous mutants containing the same point mutation in rpoB gene. CC09 is the WT strain of B. velezensis. + or – indicates the strain resistant or sensitive to Rif. NA means not applied in the experiment.