Fig. 6. miR-200b and miR-217 regulate the response to anti-cancer drugs.

(A) MDA-MB-231 cells were transfected with control vector (1μg), miR-200b (1 μg) or miR-217 (1 μg). The next day, cells were treated with the indicated anti-cancer drug (2 μM for celastrol; 150μM for cisplatin; 50 nM for docetaxel) for 24 h, followed by Western blot analysis. (B) MCF-7 cells were transfected with the indicated inhibitor (each at 10 nM), followed by Western blot analysis.